Newsletter
Published: 28 Nov 2025, 18:02 IST — Updated: 28 Nov 2025, 18:03 IST

In this week’s PharmaSignal Weekly Brief – Global Pharma Roundup, significant M&A activity, key regulatory approvals, and notable pipeline developments shaped the global pharma landscape. Meanwhile, pricing decisions and policy shifts continue to influence market dynamics and strategic positioning.

M&A and Strategic Deals

  • Johnson & Johnson’s acquisition of Halda Therapeutics for $3.05B expands its footprint in the metabolic disease space.
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  • Biogen’s partnership with Dayra aims to enhance its immunological disease portfolio, indicating a strategic focus on immune-mediated conditions.
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Regulatory and Approvals

  • Otsuka secured FDA approval for Voyxact in kidney disease, marking a significant step in addressing this unmet medical need.
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  • Regeneron’s Eylea HD received FDA approvals, potentially strengthening its market position in the eye care segment.
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Pipeline and R&D Highlights

  • Kelun and Merck’s ADC shows promise in lung cancer treatment, potentially offering a new therapeutic option for patients.
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  • Bayer’s Asundexian trial shows promise in stroke prevention, potentially adding a new weapon to the arsenal against this prevalent condition.
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Market, Pricing and Policy Signals

  • Novo Nordisk’s launch of Wegovy at $349 signals a competitive pricing strategy in the obesity market.
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  • The CMS setting 2027 Medicare prices for Wegovy and Trelegy could have far-reaching implications for these drugs’ market access and uptake.
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