Newsletter
Published: 4 Sep 2025, 23:11 IST — Updated: 6 Sep 2025, 11:36 IST

• Novartis licenses RNA medicine from Arrowhead for $200 million.
• The deal targets preclinical RNA medicine for Parkinson’s disease.
• Novartis aims to advance treatment options for neurodegenerative diseases.

Novartis has entered into a licensing agreement with Arrowhead Pharmaceuticals, securing access to a preclinical RNA medicine designed to combat neurodegenerative diseases such as Parkinson’s. The deal is valued at a minimum of $200 million, highlighting Novartis’s commitment to expanding its pipeline in the field of neurological disorders. This agreement grants Novartis the rights to develop and commercialize the RNA-based therapeutic globally.

The collaboration focuses on leveraging Arrowhead’s expertise in RNA interference (RNAi) technology, which aims to silence specific genes involved in disease progression. This approach could potentially offer new treatment avenues for patients with Parkinson’s disease, a condition affecting over 10 million people worldwide. By targeting the underlying genetic causes, Novartis hopes to address unmet medical needs in this challenging therapeutic area.

Arrowhead will receive an upfront payment as part of the $200 million deal, with potential milestone payments and royalties on future sales. Although specific financial terms beyond the initial payment remain undisclosed, the partnership underscores the growing interest in RNA-based therapies within the pharmaceutical industry. Novartis’s investment reflects its strategic focus on innovative treatments that could transform the management of neurodegenerative diseases.

This licensing agreement is part of Novartis’s broader strategy to enhance its portfolio through strategic collaborations and acquisitions. The company has been actively pursuing opportunities to strengthen its position in the neuroscience sector, as evidenced by recent deals and partnerships. For more information on similar transactions, visit our Mergers & Acquisitions section.

For further details on Novartis and its initiatives, visit the Novartis website. Additionally, explore our Drug Approvals page for updates on regulatory developments and new therapies entering the market.