Newsletter
Published: 23 Nov 2025, 20:39 IST — Updated: 24 Nov 2025, 23:11 IST

In this week’s PharmaSignal Weekly Brief – Global Pharma Roundup, we see a flurry of M&A activity, key regulatory approvals, and significant pipeline developments. Meanwhile, the global pharma landscape is also being shaped by important market, pricing, and policy signals.

M&A and Strategic Deals

  • Johnson & Johnson’s acquisition of Halda Therapeutics for $3.05 billion marks a significant expansion in their oncology portfolio. Read more →
  • Novo Nordisk’s $5.2 billion acquisition of Akero Therapeutics is set to boost their metabolic disease treatment offerings. Read more →

Regulatory and Approvals

  • Arrowhead’s Redemplo received FDA approval, marking a significant advancement in gene therapy. Read more →
  • Regeneron secured FDA approvals for Eylea HD, potentially strengthening its position in the eye care market. Read more →

Pipeline and R&D Highlights

  • Pfizer’s mRNA flu shot has shown superior efficacy in trials, potentially reshaping the flu vaccine market. Read more →
  • Roche’s Giredestrant has shown promise in a breast cancer study, potentially offering a new treatment option. Read more →

Market, Pricing and Policy Signals

  • Amgen’s decision to cut the price of Repatha by 60% in the U.S. signals a strategic shift in response to market pressures. Read more →
  • The FDA’s launch of a domestic generic drug fast-track review program could significantly impact the generic drug market. Read more →

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